New review in FEMS on the origin and adaptation of P. falciparum and P. vivax
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Review of the existing body of knowledge, including current research dealing with these questions, focusing particularly on genetic analysis and genomic variability of these parasites and comparison with related Plasmodium species infecting other species of host (such as non-human primates).
Abstract.
Malaria is considered one of the most important scourges that humanity has faced during its history, being responsible every year for numerous deaths worldwide. The disease is caused by protozoan parasites, among which two species are responsible of the majority of the burden, Plasmodium falciparum and Plasmodium vivax. For these two parasite species, the questions of their origin (how and when they appeared in humans), of their spread throughout the world, as well as how they have adapted to humans have long been of interest to the scientific community. Here, we review the current knowledge that has accumulated on these different questions, thanks in particular to the analysis of the genetic and genomic variability of these parasites and comparison with related Plasmodium species infecting other host species (like non-human primates). In this paper we review the existing body of knowledge, including current research dealing with these questions, focusing particularly on genetic analysis and genomic variability of these parasites and comparison with related Plasmodium species infecting other species of host (such as non-human primates).
“Key words: Malaria, host switch, colonization, local adaptation, comparative and population genomics, vectors.”
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Comments (6)
Carol Robinzine
This is a really good tip particularly to those new to the blogosphere. Short but very accurate info… Thank you for sharing this one. A must read article!
Virginie
Thank you very much for your comment!
israel-lady.co.il
Im very pleased to find this site. I need to to thank you for ones time for this particularly fantastic read!! I definitely really liked every part of it and I have you bookmarked to see new information on your site.
Twicsy
Wow that was strange. I just wrote an very long comment but
after I clicked submit my comment didn’t appear. Grrrr… well I’m not writing
all that over again. Anyway, just wanted to say great blog!
Virginie
Thank you very much for your message! Much appreciate your comment!