Nature Microbiology (2018) Genomes of all known members of a Plasmodium subgenus reveal paths to virulent human malaria Abstract Plasmodium falciparum, the most virulent agent of human malaria, shares a recent common ancestor with the gorilla parasite Plasmodium praefalciparum. Little is known about the other gorilla- and chimpanzee-infecting species in the same (Laverania) subgenus as […]
FEMS Microbiology Reviews, fuab047 (2021) A population genetic perspective on the origin, spread and adaptation of the human malaria agents Plasmodium falciparum and Plasmodium vivax Abstract Malaria is considered one of the most important scourges that humanity has faced during its history, being responsible every year for numerous deaths worldwide. The disease is caused by […]
PLOS Biology (2018) Plasmodium vivax-like genome sequences shed new insights into Plasmodium vivax biology and evolution Abstract Although Plasmodium vivax is responsible for the majority of malaria infections outside Africa, little is known about its evolution and pathway to humans. Its closest genetic relative, P. vivax-like, was discovered in African great apes and is hypothesized […]
Science Advances. 7 : eabc3713 (2021) Population genomic evidence of Plasmodium vivax Southeast Asian origin Abstract Plasmodium vivax is the most common and widespread human malaria parasite. It was recently proposed that P. vivax originates from sub-Saharan Africa based on the circulation of its closest genetic relatives (P. vivax-like) among African great apes. However, the limited number of […]
